Businesses for Sale in Port St. Lucie, FL

Find Main Street businesses for sale in Port St. Lucie. Use Bizgora’s map and local market intelligence to evaluate each opportunity before you inquire.

Thousands of businesses for sale in Port St. Lucie — showing a sample of listings below.

Featured listings

For Sale Full-Service Restaurants

1,400 SF Full-Service Plaza Restaurant

Port Saint Lucie, FL

$125K Asking Price
Cash Flow $75K
Gross Revenue $325K
EBITDA $14K
For Sale General Medical Practices

Hospital-Adjacent Pharmacy with On-Site Blood Lab

Port Saint Lucie, FL

$300K Asking Price
Cash Flow $100K
Gross Revenue $3.65M
EBITDA $493K
For Sale Pizzerias

Chicago-Style Pizza & Sports Tavern

Port Saint Lucie, FL

$400K Asking Price
Cash Flow $100K
Gross Revenue $1.35M
EBITDA $74K
For Sale Beauty Salons

Lash & Beauty Studio

Port Saint Lucie, FL

$100K Asking Price
Cash Flow $50K
Gross Revenue $400K
EBITDA $28K
For Sale Full-Service Restaurants

Cocktail Pub

Port Saint Lucie, FL

$550K Asking Price
Cash Flow $275K
Gross Revenue $2.55M
EBITDA $107K
For Sale General Medical Practices

Aesthetic Practice

Port Saint Lucie, FL

$550K Asking Price
Cash Flow $250K
Gross Revenue $400K
EBITDA $54K
For Sale Courier & Delivery Services

Luxury Furniture Logistics

Port Saint Lucie, FL

$1.2M Asking Price
Cash Flow $325K
Gross Revenue $1.6M
EBITDA $107K
For Sale Carpet Cleaning Companies

Floor Care

Port Saint Lucie, FL

$150K Asking Price
Cash Flow $25K
Gross Revenue $75K
EBITDA $11K
For Sale Home Health Care

Home Care

Port Saint Lucie, FL

$1.2M Asking Price
Cash Flow $375K
Gross Revenue $2.65M
EBITDA $199K
For Sale Office Cleaning & Janitorial

Home Cleaning

Port Saint Lucie, FL

$75K Asking Price
Cash Flow $25K
Gross Revenue $50K
EBITDA $3K
For Sale Home Health Care

Sports Fundraising

Port Saint Lucie, FL

$50K Asking Price
Cash Flow $25K
Gross Revenue $275K
EBITDA $21K
For Sale Electrical Repair Companies

Computer Sales Service

Port Saint Lucie, FL

$750K Asking Price
Cash Flow $100K
Gross Revenue $700K
EBITDA $43K
For Sale Plumbing Companies

Commercial Plumbing

Port Saint Lucie, FL

$1.2M Asking Price
Cash Flow $375K
Gross Revenue $2.3M
EBITDA $90K
For Sale Pet Care Services

Pet Grooming Spa

Port Saint Lucie, FL

$400K Asking Price
Cash Flow $125K
Gross Revenue $600K
EBITDA $69K
For Sale HVAC (Heating & Cooling) Companies

Commercial HVAC Operation with Recurring Service Contracts

Port Saint Lucie, FL

$4.0M Asking Price
Cash Flow $650K
Gross Revenue $3.6M
EBITDA $191K
For Sale Consulting Firms

Cannabis Card Consulting

Port Saint Lucie, FL

$250K Asking Price
Cash Flow $125K
Gross Revenue $200K
EBITDA $21K
For Sale Beauty Salons

Beauty Salon

Port Saint Lucie, FL

$300K Asking Price
Cash Flow $50K
Gross Revenue $650K
EBITDA $46K
For Sale General Medical Practices

Multi-Service Wellness & Hormone Therapy Clinic

Port Saint Lucie, FL

$150K Asking Price
Cash Flow $100K
Gross Revenue $150K
EBITDA $20K
For Sale General Medical Practices

Medical Spa

Port Saint Lucie, FL

$2.55M Asking Price
Cash Flow $650K
Gross Revenue $1.95M
EBITDA $263K
For Sale IT Services & Tech Support

Managed IT Services

Port Saint Lucie, FL

$200K Asking Price
Cash Flow $75K
Gross Revenue $150K
EBITDA $20K
For Sale IT Services & Tech Support

Retail Pharmacy

Port Saint Lucie, FL

$1.65M Asking Price
Cash Flow $400K
Gross Revenue $5.4M
EBITDA $702K
For Sale HVAC (Heating & Cooling) Companies

Multi-Account Commercial Refrigeration & HVAC Service

Port Saint Lucie, FL

$800K Asking Price
Cash Flow $325K
Gross Revenue $1.65M
EBITDA $87K
For Sale Dental Practices

Dental Med Spa

Port Saint Lucie, FL

$3.5M Asking Price
Cash Flow $375K
Gross Revenue $950K
EBITDA $148K
For Sale Beauty Salons

Lash Studio

Port Saint Lucie, FL

$400K Asking Price
Cash Flow $125K
Gross Revenue $300K
EBITDA $21K
For Sale Women's Clothing Store

Luxury Boutique

Port Saint Lucie, FL

$4.5M Asking Price
Cash Flow $1.45M
Gross Revenue $5.6M
EBITDA $207K
For Sale Women's Clothing Store

Women's Apparel

Port Saint Lucie, FL

$4.75M Asking Price
Cash Flow $1.25M
Gross Revenue $5.9M
EBITDA $218K
For Sale Nail Salons

Nail Salon

Port Saint Lucie, FL

$800K Asking Price
Cash Flow $350K
Gross Revenue $1.25M
EBITDA $213K
For Sale Beauty Salons

Beauty Salon

Port Saint Lucie, FL

$75K Asking Price
Cash Flow $75K
Gross Revenue $100K
EBITDA $7K
For Sale Auto Repair Shops

Auto Repair

Port Saint Lucie, FL

$950K Asking Price
Cash Flow $300K
Gross Revenue $950K
EBITDA $58K
For Sale Beauty Salons

Beauty Salon

Port Saint Lucie, FL

$50K Asking Price
Cash Flow $50K
Gross Revenue $125K
EBITDA $9K
For Sale Physical Therapy

Wellness Studio

Port Saint Lucie, FL

$400K Asking Price
Cash Flow $175K
Gross Revenue $550K
EBITDA $57K
For Sale General Contractors

Tree Service

Port Saint Lucie, FL

$600K Asking Price
Cash Flow $275K
Gross Revenue $1.7M
EBITDA $58K
For Sale Beauty Salons

Multi-Unit Salons

Port Saint Lucie, FL

$2.6M Asking Price
Cash Flow $300K
Gross Revenue $3.25M
EBITDA $231K
For Sale Italian Restaurants

Italian Cafe Bakery

Port Saint Lucie, FL

$550K Asking Price
Cash Flow $200K
Gross Revenue $1.05M
EBITDA $58K
For Sale Hotels & Motels

Wellness Spa

Port Saint Lucie, FL

$500K Asking Price
Cash Flow $175K
Gross Revenue $475K
EBITDA $93K
For Sale Pet Care Services

Dog Grooming Retail

Port Saint Lucie, FL

$300K Asking Price
Cash Flow $25K
Gross Revenue $400K
EBITDA $46K
For Sale Landscaping & Lawn Care

Commercial Lawn Care

Port Saint Lucie, FL

$75K Asking Price
Cash Flow $50K
Gross Revenue $75K
EBITDA $7K
For Sale General Contractors

Outdoor Structures

Port Saint Lucie, FL

$2.5M Asking Price
Cash Flow $500K
Gross Revenue $1.85M
EBITDA $63K
For Sale General Medical Practices

Membership-Based Longevity & Medical Wellness Clinic

Port Saint Lucie, FL

$800K Asking Price
Cash Flow $350K
Gross Revenue $1.7M
EBITDA $230K
For Sale Nail Salons

Nail Salon

Port Saint Lucie, FL

$75K Asking Price
Cash Flow $25K
Gross Revenue $325K
EBITDA $55K
For Sale General Medical Practices

Adult Medical Clinic

Port Saint Lucie, FL

$150K Asking Price
Cash Flow $50K
Gross Revenue $250K
EBITDA $34K
For Sale Furniture Stores

Upholstery Shop

Port Saint Lucie, FL

$150K Asking Price
Cash Flow $75K
Gross Revenue $125K
EBITDA $5K
For Sale Auto Parts Stores

Custom Parts

Port Saint Lucie, FL

$175K Asking Price
Cash Flow $75K
Gross Revenue $500K
EBITDA $37K
For Sale Gift Shops

Gourmet Treats

Port Saint Lucie, FL

$400K Asking Price
Cash Flow $175K
Gross Revenue $700K
EBITDA $35K
For Sale eCommerce / Online Retailers

Flower Shop

Port Saint Lucie, FL

$250K Asking Price
Cash Flow $275K
Gross Revenue $450K
EBITDA $27K
For Sale eCommerce / Online Retailers

Flower Shop

Port Saint Lucie, FL

$150K Asking Price
Cash Flow $125K
Gross Revenue $275K
EBITDA $16K
For Sale Dog Walking/Pet Sitting/Other

Pet Grooming Retail

Port Saint Lucie, FL

$100K Asking Price
Cash Flow $25K
Gross Revenue $300K
EBITDA $35K
For Sale Accounting/Tax

Tax Services

Port Saint Lucie, FL

$200K Asking Price
Cash Flow $225K
Gross Revenue $75K
EBITDA $14K
For Sale Dog Walking/Pet Sitting/Other

Local Deli

Port Saint Lucie, FL

$200K Asking Price
Cash Flow $25K
Gross Revenue $400K
EBITDA $46K
For Sale Jewelry Stores

Jewelry Store

Port Saint Lucie, FL

$6.0M Asking Price
Cash Flow $125K
Gross Revenue $1.65M
EBITDA $56K

Showing a sample of listings below. Explore thousands on the map.

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Frequently asked questions

How many businesses for sale are listed in Port St. Lucie, FL?

Bizgora currently shows 69 businesses for sale matching this search. The page previews up to 50; open the map to browse the full set.

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Bizgora is map-first. Every opportunity can be evaluated with local market context — neighborhood demographics, nearby competition, and traffic signals — so buyers diligence deals with more than asking price alone.

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Yes. Bizgora covers Main Street businesses for sale across the United States.